Industry News

NR as a Promising Therapeutic Candidate for Alpers' Disease
NR as a Promising Therapeutic Candidate for Alpers' Disease

Introduction Alpers' disease is both a neurodegenerative disorder and a metabolic disorder, which is tightly linked to mitochondrial dysfunction and mutations in the catalytic subunit of polymerase

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Deep Insight on NADH: a Potential Medical Arsenal
Deep Insight on NADH: a Potential Medical Arsenal

  Introduction NADH (reduced form of NAD+) serves as a carrier of biological hydrogen and an electron donor, which participates in diverse physiological processes such as protein synthesis, DNA repair,

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Frontier Dynamics on the Molecular Mechanism of Ginsenoside Rh2 Against Tumor
Frontier Dynamics on the Molecular Mechanism of Ginsenoside Rh2 Against Tumor

  Introduction Ginsenoside Rh2, one protopanaxadiol (PPD)-type rare ginsenoside in Panax ginseng, is uncovered to possibly have broad-spectrum pharmacological activity in diversified tumors. It is utili

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SLC25A51 Functions as an NAD+/NADH Redox Decoupler in AML
SLC25A51 Functions as an NAD+/NADH Redox Decoupler in AML

Introduction Solute carrier family 25 member 51 (SLC25A51) is perceived as a mammalian transporter, which is capable of importing oxidized nicotinamide adenine dinucleotide (NAD+) into mitochondrial matrix. Remark

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The Molecular Mechanisms Underlying the Interaction Between NAD+/NMN and DBC1
The Molecular Mechanisms Underlying the Interaction Between NAD+/NMN and DBC1

Introduction Oxidized form of nicotinamide adenine dinucleotide (NAD+) and its precursor nicotinamide mononucleotide (NMN) have been uncovered to restore DNA repair and prevent cancer progression via the deleted i

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Protective Role of NAD+ Against MI-induced HF in Sprague-Dawley Rats and Beagles
Protective Role of NAD+ Against MI-induced HF in Sprague-Dawley Rats and Beagles

1. Introduction Disrupted nicotinamide adenine dinucleotide (NAD+) metabolism is increasingly deemed to be one of risk factor for amendable cardiovascular disorders. A substantial evidence has mirrored that res

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Investigating the Great Possibility of Rare Ginsenosides as Drugs and Nutraceuticals
Investigating the Great Possibility of Rare Ginsenosides as Drugs and Nutraceuticals

1. Introduction Rare ginsenosides, a group of dammarane triterpenoids that exist in low natural abundance, fuels a high concern from scholars recently, showing great potential as shining components in drugs and nu

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Maternal NAD Precursor Supplementation to Reduce the Risk of Developing CNDD
Maternal NAD Precursor Supplementation to Reduce the Risk of Developing CNDD

1. Introduction Nicotinamide adenine dinucleotide (NAD) has been unveiled to be essential for embryonic development. Patients with genetic variants in the NAD+ de novo synthesis pathway often have congen

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Further Exploration on the Effects of Sweetener Stevia on Human Gut Microbiota
Further Exploration on the Effects of Sweetener Stevia on Human Gut Microbiota

1. Introduction The gut microbiota has long been regarded as one of the key elements contributing to the regulation of host health. Any changes in the composition or quality of the gut microbiota may have physiolo

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